The suggested answer is A, D, E.
To interact with elements in a web application, the element does not need to be visible on the screen as long as it exists on the currently loaded page, making interaction possible. Win32 mode can be used to identify the Internet Explorer window specifically, ensuring accurate recognition of the browser window. HTML spy mode can be used to identify HTML elements in major browser applications like Internet Explorer, Edge, Firefox, and Chrome, but not all browser applications.