When migrating to an Autonomous Database using Oracle Data Pump, you need to use specific parameters to ensure compatibility and proper data transformation. The parameters TRANSFORM=DWCS_CVT_IOTS:Y and TRANSFORM=SEGMENT_ATTRIBUTES:N are essential for converting index-organized tables and excluding segment attributes, respectively. REMAP_TABLESPACE=%:DATA is necessary to map tablespaces to the Autonomous Database default. Additionally, TRANSPORTABLE=ALWAYS is used to specify the transportable tablespace method, which is often required for efficient migrations to Autonomous Database.