Before running the GenPluginCfg command, it is important to ensure that a web server definition is created. This can be accomplished by using either the Integrated Solutions Console or the ConfigurewebServerDefinition.jacl script. This step ensures that the web server configuration is correctly set up to generate the plugin-cfg.xml file. Deleting the plugin-cfg.xml file or clearing specific options may not address the core requirement of having a web server definition in place.