Correct Answer: CDFor pre-training a large language model with custom TensorFlow operations and a large batch size on Google Cloud, using a configuration with multiple high-GPU machines and tf.distribute.MultiWorkerMirroredStrategy would be the optimal choice. Although TPUs provide excellent performance, they are not the best fit for tasks involving custom TensorFlow operations, as stated in the Google Cloud documentation. Among the remaining options, the configuration that balances training speed and cost-effectiveness involves using 16 workers of a2-highgpu-8g machines. Using tf.distribute.MultiWorkerMirroredStrategy with these high-GPU machines ensures efficient parallel training by distributing the workload across multiple GPUs while handling the large batch size effectively.