D is the correct answer.
Explanation:
To automate the promotion of a read replica to the primary instance in the event of a failure, we need to detect the failure and then invoke an AWS Lambda function to promote the replica instance. This can be achieved using Amazon EventBridge.
Option A is incorrect because using a CNAME with health checks doesn't provide an automated way to promote the read replica. Additionally, subscribing an Amazon SNS topic to Amazon RDS failure notifications from AWS CloudTrail doesn't help to promote the replica.
Option B is incorrect because a custom endpoint is not required to promote the read replica. Additionally, using AWS CloudTrail to run an AWS Lambda function to promote the replica instance doesn't provide an automated way to update the application endpoint to point to the newly promoted instance.